James E. Gern, MD  
James E. Gern, MD close
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James E. Gern, MD Print Friendly Page

Faculty, University of Wisconsin School of Medicine and Public Health

Dr. Gern is board-certified in Allergy and Immunology and Pediatrics. His areas of interest include childhood allergies, asthma, food allergies, and immune deficiency.

Specialties

Pediatric Allergy, Asthma and Immunology

Allergic Rhinitis

Allergy Testing

Asthma

Atopic Dermatitis/Eczema

Drug Allergies

Food Allergy

Immunodeficiency Disorders

Immunotherapy

Insect Sting Allergy

Latex Allergies

Patch Testing

Preschool Wheezing

Pulmonary Function Test

Recurrent Sinus Infection

Uticaria

Clinics

American Family Children's Hospital
(608) 263-6420 | (800) 323-8942 | Map

UW School of Medicine and Public Health

Department of Pediatrics
Department of Medicine

Professional Certifications and Education

Board Certification Allergy & Immunology
Pediatrics
Fellowship The Johns Hopkins Hospital, Baltimore, MD
Internship State University of New York Upstate Medical University, Syracuse, NY
Medical School University of South Florida, Tampa, FL

Medical interpreters are available to help patients communicate with hospital and clinic staff. For more information, please contact interpreter services at (608) 262-9000.
Research

Dr. Gern leads several NIH-funded studies to define the role of viral infections in the initiation and disease activity of asthma, and to identify interactions between host and viral factors that determine the severity of respiratory illnesses. He is the Principal Investigator for the University of Wisconsin Asthma and Allergic Diseases Clinical Research Center.


PubMed Articles
Hallmark B Wegienka G Havstad S Billheimer D Ownby D Mendonca EA Gress L Stern DA Myers JB Khurana Hershey GK Hoepner L Miller RL Lemanske RF Jackson DJ Gold DR O'Connor GT Nicolae DL Gern JE Ober C Wright AL Martinez FD Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood. Am J Respir Crit Care Med . 2021 Apr 1;203(7):864-870
[PubMed ID: 33535024]
Choi T Devries M Bacharier LB Busse W Camargo CA Jr Cohen R Demuri GP Evans MD Fitzpatrick AM Gergen PJ Grindle K Gruchalla R Hartert T Hasegawa K Khurana Hershey GK Holt P Homil K Jartti T Kattan M Kercsmar C Kim H Laing IA LeBeau P Lee KE Le Souëf PN Liu A Mauger DT Ober C Pappas T Patel SJ Phipatanakul W Pongracic J Seroogy C Sly PD Tisler C Wald ER Wood R Gangnon R Jackson DJ Lemanske RF Jr Gern JE Bochkov YA Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection. Am J Respir Crit Care Med . 2021 Apr 1;203(7):822-830
[PubMed ID: 33357024]
Altman MC Calatroni A Ramratnam S Jackson DJ Presnell S Rosasco MG Gergen PJ Bacharier LB O'Connor GT Sandel MT Kattan M Wood RA Visness CM Gern JE Inner City Asthma Consortium. Endotype of Allergic Asthma with Airway Obstruction in Urban Children. J Allergy Clin Immunol . 2021 Mar 10;
[PubMed ID: 33713771]
Ramratnam S Lockhart A Visness CM Calatroni A Jackson DJ Gergen PJ Bacharier LB O'Connor GT Sandel MT Kattan M Wood RA Gern JE Inner City Asthma Consortium. Maternal Stress and Depression are Associatedwith Respiratory Phenotypes in Urban Children. J Allergy Clin Immunol . 2021 Mar 10;
[PubMed ID: 33713764]
LeBeau P Lockhart A Togias A Sandel MT Gereige JD Bacharier L Lovinsky-Desir S Wood RA James R Busse WW Gern JE Altman MC National Institute of Allergy and Infectious Diseases-Sponsored Inner-City Asthma Consortium. Cockroach-induced IL9, IL13, and IL31 expression and the development of allergic asthma in urban children. J Allergy Clin Immunol . 2021 Mar 9;
[PubMed ID: 33712279]
Lane Starr NM Evans MD Lee KE Gern JE Denlinger LC Ensemble Analysis Identifies Nasal 15-Keto-PGE2 as a Predictor of Recovery in Experimental Rhinovirus Colds. J Infect Dis . 2021 Mar 3;
[PubMed ID: 33681993]
Schmit KM Brown R Hayer S Checovich MM Gern JE Wald ER Barrett B Wisconsin Upper Respiratory Symptom Survey for Kids: Validation of an Illness-specific Quality of Life Instrument. Pediatr Res . 2021 Feb 24;
[PubMed ID: 33627821]
Rudman Spergel AK Sever ML Johnson J Gill MA Schulten V Frazier A Kercsmar CM Lovinsky-Desir S Searing DA Sette A Shao B Teach SJ Gern JE Busse WW Togias A Wood RA Liu AH National Institute of Allergy and Infectious Diseases Inner City Asthma Consortium. Development of nasal allergen challenge with cockroach in children with asthma. Pediatr Allergy Immunol . 2021 Feb 19;
[PubMed ID: 33606312]
Mansbach JM Geller RJ Hasegawa K Piedra PA Avadhanula V Gern JE Bochkov YA Espinola JA Sullivan AF Camargo CA Detection of Respiratory Syncytial Virus or Rhinovirus Weeks After Hospitalization for Bronchiolitis and the Risk of Recurrent Wheezing. J Infect Dis . 2021 Feb 3;223(2):268-277
[PubMed ID: 32564083]
Turi KN McKennan C Gebretsadik T Snyder B Seroogy CM Lemanske RF Jr Zoratti E Havstad S Ober C Lynch S McCauley K Yu C Jackson DJ Gern JE Hartert TV ECHO-CREW investigators. Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma. J Allergy Clin Immunol . 2021 Jan 10;
[PubMed ID: 33434532]
Dunlop AL Essalmi AG Alvalos L Breton C Camargo CA Cowell WJ Dabelea D Dager SR Duarte C Elliott A Fichorova R Gern J Hedderson MM Thepaksorn EH Huddleston K Karagas MR Kleinman K Leve L Li X Li Y Litonjua A Ludena-Rodriguez Y Madan JC Nino JM McEvoy C O'Connor TG Padula AM Paneth N Perera F Sathyanarayana S Schmidt RJ Schultz RT Snowden J Stanford JB Trasande L Volk HE Wheaton W Wright RJ McGrath M program collaborators for Environmental Influences on Child Health Outcomes. Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: Findings from the ECHO cohorts. PLoS One . 2021;16(1):e0245064
[PubMed ID: 33418560]
Bunis DG Bronevetsky Y Krow-Lucal E Bhakta NR Kim CC Nerella S Jones N Mendoza VF Bryson YJ Gern JE Rutishauser RL Ye CJ Sirota M McCune JM Burt TD Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells. Cell Rep . 2021 Jan 5;34(1):108573
[PubMed ID: 33406429]
Agache I Akdis CA Akdis M Canonica GW Casale T Chivato T Corren J Chu DK Del Giacco S Eiwegger T Flood B Firinu D Gern JE Hamelmann E Hanania N Hernández-Martín I Knibb R Mäkelä M Nair P O'Mahony L Papadopoulos NG Papi A Park HS Pérez de Llano L Pfaar O Quirce S Sastre J Shamji M Schwarze J Palomares O Jutel M EAACI Biologicals Guidelines-Recommendations for severe asthma. Allergy . 2021 Jan;76(1):14-44
[PubMed ID: 32484954]
Ahluwalia TS Eliasen AU Sevelsted A Pedersen CT Stokholm J Chawes B Bork-Jensen J Grarup N Pedersen O Hansen T Linneberg A Sharma A Weiss ST Evans MD Jackson DJ Morin A Krogfelt KA Schjørring S Mortensen PB Hougaard DM Bybjerg-Grauholm J Bækvad-Hansen M Mors O Nordentoft M Børglum AD Werge T Agerbo E Gern JE Lemanske RF Jr Ober C Pedersen AG Bisgaard H Bønnelykke K FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses. Nat Commun . 2020 Dec 16;11(1):6398
[PubMed ID: 33328473]
Steiman CA Evans MD Lee KE Lasarev MR Gangnon RE Olson BF Barnes KL Bendixsen CG Seroogy CM Gern JE Patterns of farm exposure are associated with reduced incidence of atopic dermatitis in early life. J Allergy Clin Immunol . 2020 Dec;146(6):1379-1386.e6
[PubMed ID: 32650021]
Helling BA Sobreira DR Hansen GT Sakabe NJ Luo K Billstrand C Laxman B Nicolae RI Nicolae DL Bochkov YA Gern JE Nobrega MA White SR Ober C Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma. Commun Biol . 2020 Nov 13;3(1):678
[PubMed ID: 33188283]
Raita Y Camargo CA Jr Bochkov YA Celedón JC Gern JE Mansbach JM Rhee EP Freishtat RJ Hasegawa K Integrated-omics endotyping of infants with rhinovirus bronchiolitis and risk of childhood asthma. J Allergy Clin Immunol . 2020 Nov 13;
[PubMed ID: 33197460]
Jackson DJ Busse WW Togias A Gern JE Altman MC Reply. J Allergy Clin Immunol . 2020 Nov;146(5):1214-1215
[PubMed ID: 32828589]
Tang HHF Lang A Teo SM Judd LM Gangnon R Evans MD Lee KE Vrtis R Holt PG Lemanske RF Jr Jackson DJ Holt KE Inouye M Gern JE Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk. J Allergy Clin Immunol . 2020 Oct 19;
[PubMed ID: 33091409]
Sheehan WJ Krouse RZ Calatroni A Gergen PJ Gern JE Gill MA Gruchalla RS Khurana Hershey GK Kattan M Kercsmar CM Lamm CI Little FF Makhija MM Searing DA Zoratti E Busse WW Teach SJ NIAID-sponsored Inner-City Asthma Consortium. Aeroallergen Sensitization, Serum IgE, and Eosinophilia as Predictors of Response to Omalizumab Therapy During the Fall Season Among Children with Persistent Asthma. J Allergy Clin Immunol Pract . 2020 Oct;8(9):3021-3028.e2
[PubMed ID: 32376491]
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